Glycoprotein VI (GPVI) is a platelet surface receptor for collagen exposed to the blood following platelet adhesion via GPIb-IX-V complex-vWF interaction on damage to the endothelium. GPVI receptors form dimers on ligand binding and induces signal transduction via an immunorecep...
Background and Objectives: Genetic factors that affect warfarin dose are not routinely evaluated in the Korean population. In this study, we investigated the influence of genetic polymorphisms (GPs) on optimal warfarin dose (OWD) and derived an OWD prediction algorithm based on ...
Purpose: Voriconazole has been shown to interfere with the anticoagulant efficacy of warfarin. The package insert warns of the risk of prolonged bleeding times when prescribing the drug. We report a case that resulted in the successful management of this interaction by warfarin ...
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